Stereo Dissecting Microscope
all about Stereo Dissecting MicroscopeThe 2008 Garrod Lecture: Antimicrobial resistance--animals and the environment
The 2008 Garrod Lecture: Antimicrobial resistance--animals and the environment
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The evolution of resistance to microbes is one of the most significant problems in modern medicine, posing serious threats to human and animal health. The early work on the use of antibiotics to bacterial infections gave much hope that infectious diseases were no longer a problem, especially in the human field. However, as their use, indeed over-use, progressed, resistance (both monoresistance and multiresistance), which was often transferable between different strains and species of bacteria, emerged. In addition, the situation is increasingly complex, as various mechanisms of resistance, including a wide range of β-lactamases, are now complicating the issue.
The use of antibiotics in animals, especially those used for growth promotion, has come in for serious criticism, especially those where their use should be reserved for difficult human infections. To lend control, certain antibiotic growth promoters have been banned from use in the EU and the UK.
Antimicrobial resistance is not confined to bacteria but occurs in viruses, protozoa and helminths. In many of these, the mechanism of resistance is unknown, and hence their control is still in question. It is likely, however, that the mechanisms are no less complicated than those pertaining to bacteria.
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| • | Differential transferrin expression in placentae from normal and abnormal pregnancies: a pilot study |
| Background: The placenta is an important site for iron metabolism in humans. It transfers iron from the mother to the fetus. One of the major iron transport proteins is transferrin, which is a blood plasma protein crucial for iron uptake. Its localization and expression may be one of the markers to distinguish placental dysfunction. Methods: In the experimental study we used antibody preparation, mass spectrometric analysis, biochemical and immunocytochemical methods for characterization of transferrin expression on the human choriocarcinoma cell line JAR (JAR cells), placental lysates, and cryostat sections. Newly designed monoclonal antibody TRO-tf-01 to human transferrin was applied on human placentae from normal (n = 3) and abnormal (n = 9) pregnancies. Results: Variations of transferrin expression were detected in villous syncytiotrophoblast, which is in direct contact with maternal blood. In placentae from normal pregnancies, the expression of transferrin in the syncytium was significantly lower (p < 0.001) when compared to placentae from abnormal ones (gestational diabetes, pregnancy induced hypertension, drug abuse). Conclusion: These observations suggest that in the case of abnormal pregnancies, the fetus may require higher levels of transferrin in order to prevent iron depletion due to the stress from the placental dysfunction. | |
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| • | 'Oosight' Microscope Enables Embryonic Stem Cell Breakthrough |
| A noninvasive, polarized light microscope invented at the Marine Biological Laboratory played a crucial role in a recent breakthrough in embryonic stem-cell research aimed at developing medical therapies. Oregon Health & Science University recently reported the successful derivation of stem cells from cloned monkey embryos. While embryonic stem cells have been made from cloned embryos in a mouse, this is the first time they have been produced in a primate. | |
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| • | A Colorful Approach to Solar Energy |
| Revisiting a once-abandoned technique, engineers at the Massachusetts Institute of Technology (MIT) have successfully created a sophisticated, yet affordable, method to turn ordinary glass into a high-tech solar concentrator. (2008-07-11) | |
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| • | Ekkyo Describes the First Benefits of Controlled Hyperthermia in Humans in "Lasers in Surgery and Medicine" |
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| • | Antibody Methods and Techniques |
| Includes antibody search, methods, techniques, protocols, reviews, books, and discussion forums. | |
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| • | Stereo Microscopes with Dual Magnification, Fixed Objectives |
| Choose among quality low power stereo microscopes featuring dual magnification, fixed objectives. Discount prices! ... Stereo Microscopes Low ... | |
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